Our reviews

Our evidence

Full list:

By subtopic:

Hypertension as undesired effect of treatment (3)
Effect of adrenergic agonist oral decongestants on blood pressure (protocol stage)
Effect of amphetamines on blood pressure (protocol stage)
Effect of cyclosporine on blood pressure
Prevention of Hypertension (20)
Diet (10)
Weight loss (0)
Sodium/potassium/calcium intake (8)
Calcium supplementation for the management of primary hypertension in adults
Combined calcium, magnesium and potassium supplementation for the management of primary hypertension in adults
Calcium supplementation for prevention of primary hypertension
Effect of longer-term modest salt reduction on blood pressure
Magnesium supplementation for the management of primary hypertension in adults
Potassium supplementation for the management of primary hypertension in adults
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride
Advice to reduce dietary salt for prevention of cardiovascular disease
Garlic (1)
Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients
Caffeine (0)
Other (1)
Effect of cocoa on blood pressure
Lifestyle (4)
Exercise (3)
Community and home-based exercise for the prevention and treatment of hypertension (protocol stage)
Tai Chi for hypertension (protocol stage)
Walking for hypertension
Alcohol intake (1)
Effect of alcohol on blood pressure
Tobacco use (0)
Behavior Modification (5)
Meditation (0)
Relaxation response (1)
Relaxation therapies for the management of primary hypertension in adults
Biofeedback (0)
Advice (1)
Advice to reduce dietary salt for prevention of cardiovascular disease
Adherence (1)
Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings
Control (2)
Allied health professional-led interventions for improving control of blood pressure in patients with hypertension (protocol stage)
Interventions used to improve control of blood pressure in patients with hypertension
Preventive treatments (1)
Effect of periodontal treatments on blood pressure
Treatment of essential Hypertension (130)
Pharmacological Therapies (91)
Aldosterone antagonists (2)
Eplerenone for hypertension
Spironolactone for hypertension
General Pharmacotherapies (32)
Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension
Alpha-lipoic acid for hypertension in adults (protocol stage)
Blood pressure lowering efficacy of angiotensin receptor blockers for primary hypertension
Antiplatelet agents and anticoagulants for hypertension
First-line combination therapy versus first-line monotherapy for primary hypertension
Pharmacotherapy for mild hypertension
Beta-blockers for hypertension
Blood pressure lowering efficacy of renin inhibitors for primary hypertension
Blood pressure targets for hypertension in older adults
Blood pressure targets for the treatment of people with hypertension and cardiovascular disease
Calcium channel blockers versus other classes of drugs for hypertension
Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Long-term effects of weight-reducing drugs in people with hypertension
Pharmacotherapy for hyperuricaemia in hypertensive patients
Antihypertensive pharmacotherapy for prevention of sudden cardiac death in hypertensive individuals
Effect of phosphodiesterase 5 inhibitors on blood pressure (protocol stage)
Creatine and creatine analogues in hypertension and cardiovascular disease
First-line drug classes for hypertension in adults: a network meta-analysis (protocol stage)
Pharmacological interventions for hypertension in children
Methyldopa for primary hypertension
Pharmacological interventions for hypertensive emergencies
Pharmacotherapy for hypertension in adults 60 years or older
Pharmacotherapy for hypertension in adults with obstructive sleep apnea (protocol stage)
Statins for preventing major vascular events in people with hypertension (protocol stage)
Withdrawal of antihypertensive drugs in older people
Blood pressure targets in adults with hypertension
First-line drugs for hypertension
Evening versus morning dosing regimen drug therapy for hypertension
Pharmacotherapy for hypertension in women of different races
Pharmacotherapy for hypertension in adults aged 18 to 59 years
Pharmacotherapy for hypertension-induced left ventricular hypertrophy
Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings
Angiostensin-converting enzyme (ACE) inhibitors (7)
Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension
Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension
Angiotensin converting enzyme inhibitor induced angioedema in patients with primary hypertension (protocol stage)
Blood pressure lowering efficacy of drugs inhibiting the renin-angiotensin system as second-line therapy for primary hypertension (protocol stage)
Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension
Renin-angiotensin system inhibitors for treating COVID-19 in adults (protocol stage)
Time course for blood pressure lowering of angiotensin-converting-enzyme inhibitors (protocol stage)
Angiotensin receptor antagonists (6)
Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension
Blood pressure lowering efficacy of angiotensin receptor blockers for primary hypertension
Blood pressure lowering efficacy of drugs inhibiting the renin-angiotensin system as second-line therapy for primary hypertension (protocol stage)
Renin inhibitors versus angiotensin receptor blockers for primary hypertension (protocol stage)
Renin-angiotensin system inhibitors for treating COVID-19 in adults (protocol stage)
Time course for blood pressure lowering of angiotensin receptor blockers (protocol stage)
Beta-adrenergic blocking agents (8)
Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension
Blood pressure lowering efficacy of beta-1 selective beta blockers for primary hypertension
Beta-blockers for hypertension
Blood pressure lowering efficacy of beta-blockers as second-line therapy for primary hypertension
First-line beta-blockers versus other antihypertensive medications for chronic type B aortic dissection
Time course for blood pressure lowering of beta-blockers with partial agonist activity
Blood pressure lowering efficacy of nonselective beta-blockers for primary hypertension
Blood pressure lowering efficacy of partial agonist beta blocker monotherapy for primary hypertension
Calcium-channel blockers (5)
Blood pressure lowering efficacy of calcium channel blockers for primary hypertension (protocol stage)
Blood pressure lowering efficacy of calcium-channel blockers as second-line therapy for primary hypertension (protocol stage)
Calcium channel blockers versus other classes of drugs for hypertension
Interaction of calcium channel blockers and grapefruit juice in healthy adults (protocol stage)
Time course for blood pressure lowering of dihydropyridine calcium channel blockers
Diuretics (9)
Blood pressure lowering effect of diuretics as second line therapy for primary hypertension in crossover trials (protocol stage)
Blood pressure lowering effect of hydrochlorothiazide compared to other diuretics for hypertension (protocol stage)
Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension
Blood pressure-lowering efficacy of loop diuretics for primary hypertension
Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension
Thiazide diuretics and the risk of hip fracture
Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension
Time course for blood pressure lowering of thiazides (protocol stage)
First-line diuretics versus other classes of antihypertensive drugs for hypertension
Alpha-adrenergic blockers (2)
Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension
Blood pressure lowering efficacy of alpha blockers for primary hypertension
Central sympatholytics (2)
Blood pressure lowering efficacy of clonidine for primary hypertension (protocol stage)
Blood pressure-lowering efficacy of reserpine for primary hypertension
Direct vasodilators (1)
Hydralazine for essential hypertension
Herbs (3)
Cordyceps sinensis for hypertension in adults (protocol stage)
Roselle for hypertension in adults
Tianma Gouteng Yin Formula for treating primary hypertension
Peripheral adrenergic neuron antagonists (0)
Renin inhibitors (5)
Blood pressure lowering efficacy of renin inhibitors for primary hypertension
Blood pressure lowering efficacy of drugs inhibiting the renin-angiotensin system as second-line therapy for primary hypertension (protocol stage)
Renin inhibitors versus angiotensin converting enzyme (ACE) inhibitors for primary hypertension
Renin inhibitors versus angiotensin receptor blockers for primary hypertension (protocol stage)
Renin-angiotensin system inhibitors for treating COVID-19 in adults (protocol stage)
Statins (9)
Cerivastatin for lowering lipids
Atorvastatin for lowering lipids
Fluvastatin for lowering lipids
Lovastatin for lowering lipids (protocol stage)
Pitavastatin for lowering lipids
Pravastatin for lowering lipids
Simvastatin for lowering lipids (protocol stage)
Rosuvastatin for lowering lipids
Effect of atorvastatin on testosterone levels
Non-pharmacologic (22)
Complementary and Alternative Treatments (2)
Acupuncture for hypertension
Effect of periodontal treatments on blood pressure
Diet (10)
Weight loss (1)
Long-term effects of weight-reducing diets in people with hypertension
Sodium/potassium/calcium intake (7)
Calcium supplementation for the management of primary hypertension in adults
Combined calcium, magnesium and potassium supplementation for the management of primary hypertension in adults
Effect of longer-term modest salt reduction on blood pressure
Magnesium supplementation for the management of primary hypertension in adults
Potassium supplementation for the management of primary hypertension in adults
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride
Advice to reduce dietary salt for prevention of cardiovascular disease
Garlic (0)
Caffeine (0)
Other (2)
Effect of cocoa on blood pressure
Fermented milk for hypertension
Lifestyle (6)
Exercise (5)
Community and home-based exercise for the prevention and treatment of hypertension (protocol stage)
Interval training exercise for hypertension (protocol stage)
Isometric exercise training for hypertension (protocol stage)
Tai Chi for hypertension (protocol stage)
Walking for hypertension
Alcohol intake (1)
Alcohol intake reduction for controlling hypertension
Tobacco use (0)
Behavior Modification (4)
Meditation (0)
Relaxation response (1)
Relaxation therapies for the management of primary hypertension in adults
Biofeedback (0)
Advice (1)
Advice to reduce dietary salt for prevention of cardiovascular disease
Adherence (1)
Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings
Control (1)
Advice to reduce dietary salt for prevention of cardiovascular disease
Management/treatment of Specific sub-types of Hypertensive Patients (9)
Adolescents and young adults (0)
Children (1)
Pharmacological interventions for hypertension in children
Elderly patients (1)
Pharmacotherapy for hypertension in adults 60 years or older
Non-pregnant female patients (1)
Pharmacotherapy for hypertension in women of different races
Patients with isolated systolic hypertension (0)
Patients with renal insufficiency (1)
Blood pressure targets for hypertension in people with chronic renal disease (protocol stage)
Patients with hypertension and cardiovascular history (stroke; angina pectoris; myocardial infarction; chronic peripheral vascular occlusive disease) (0)
Patients with other cardiovascular risk factors (smoking; diabetes; high serum cholesterol levels; arterial fibrillation) (2)
Blood pressure targets for hypertension in people with diabetes mellitus
First-line drugs inhibiting the renin angiotensin system versus other first-line antihypertensive drug classes for hypertension
Resistant hypertension (1)
Pharmacotherapy for resistant hypertension in adults (protocol stage)
Special Populations (2)
First-line beta-blockers versus other antihypertensive medications for chronic type B aortic dissection
Renal denervation for resistant hypertension
Hypertensive Urgencies and Emergencies (2)
Effect of early treatment with anti-hypertensive drugs on short and long-term mortality in patients with an acute cardiovascular event
Pharmacological interventions for hypertensive emergencies
Organization of Hypertension Services (6)
Allied health professional-led interventions for improving control of blood pressure in patients with hypertension (protocol stage)
Organisational interventions for improving control of blood pressure in individuals with hypertension (protocol stage)
Screening strategies for hypertension
Self-monitoring for improving control of blood pressure in patients with hypertension (protocol stage)
Interventions for improving adherence to treatment in patients with high blood pressure in ambulatory settings
Interventions used to improve control of blood pressure in patients with hypertension

New and Updated (in the latest issue of the CLib):